MK-2206

Term ID

CHEBI:67271

Synonyms

8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one
8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one
MK 2206
MK-2206 free base
MK2206

Definition

An organic heterotricyclic compound that is [1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one substituted by 4-(1-aminocyclobutyl)phenyl and phenyl groups at positions 8 and 9, respectively. It is an allosteric Akt inhibitor.

References

cas:1032349-93-1
drugbank:DB16828
lincs.smallmolecule:LSM-1057
pubmed:30033751
pubmed:30613632
pubmed:30943918
pubmed:31463691
pubmed:31714586
pubmed:31780937
pubmed:32116708
pubmed:32194695
pubmed:32738099
pubmed:33775646
pubmed:33803402
pubmed:34122406
pubmed:34322387
pubmed:34666331
pubmed:35434236
pubmed:35457111
pubmed:35765523
pubmed:35992874
pubmed:36331743
pubmed:36359901
pubmed:36441491
pubmed:36644819
pubmed:37222135
pubmed:37521473
pubmed:37947157
pubmed:38850717
pubmed:39182598
reaxys:18391321
wikipedia.en:MK-2206

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from MK-2206

Phenotype where environments contain MK-2206

Phenotype modified by environments containing MK-2206

Phenotype affecting MK-2206

Human Disease Model