cortistatin A

Term ID

CHEBI:67171

Synonyms

(+)-cortistatin A
(1R,2R,3S,5R)-3-(dimethylamino)-17beta-(isoquinolin-7-yl)-5,8alpha-epoxy-9,19-cyclo-9,10-secoandrosta-9(11),10-diene-1,2-diol
(1R,2R,3S,5R,8alpha,17beta)-3-(dimethylamino)-17-(isoquinolin-7-yl)-5,8-epoxy-9,19-cyclo-9,10-secoandrosta-9(11),10-diene-1,2-diol

Definition

A member of the class of cortistatins that is substituted by hydroxy groups at positions 1 and 2, a dimethylamino group at the 3alpha position and an isoquinolin-7-yl group at the 17 position, with double bonds at the 9-11 and 10-19 positions (the 1R,2R,17beta enantiomer).

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: cortistatins diol secondary alcohol

cortistatins diol secondary alcohol Show first 5 Terms
inverse has_functional_parent: cortistatin B

cortistatin B Show first 5 Terms

Phenotype

Phenotype resulting from cortistatin A

Phenotype where environments contain cortistatin A

Phenotype modified by environments containing cortistatin A

Human Disease / Model Data

Citations