axitinib

Term ID

CHEBI:66910

Synonyms

• AG-013736
• axitinib
• axitinibum
• Inlyta
• N-methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide
• N-methyl-2-({3-[(E)-2-(pyridin-2-yl)vinyl]-1H-indazol-6-yl}sulfanyl)benzamide

Definition

An indazole substituted at position 3 by a 2-(pyridin-2-yl)vinyl group and at position 6 by a 2-(N-methylaminocarboxy)phenylsulfanyl group. Used for the treatment of advanced renal cell carcinoma after failure of a first line systemic treatment.

References

• cas:319460-85-0
• drugcentral:4225
• kegg.drug:D03218
• pubmed:20740300
• pubmed:21301929
• pubmed:21670972
• pubmed:22168366
• pubmed:22170007
• pubmed:22248343
• pubmed:22504156
• pubmed:22545314
• pubmed:22549112
• pubmed:22644797
• pubmed:22683928
• pubmed:22699078
• pubmed:22706540
• pubmed:22733795
• pubmed:22787405
• reaxys:11333336
• wikipedia.en:Axitinib

Ontology

ChEBI  ( EBI )