avanafil

Term ID

CHEBI:66876

Synonyms

• (S)-4-(3-Chloro-4-methoxybenzylamino)-2-(2-hydroxymethylpyrrolidin-1-yl)-N-pyrimidin-2-ylmethyl-5-pyrimidinecarboxamide
• 4-[(3-chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
• avanafil
• Stendra

Definition

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 4-[(3-chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidine-5-carboxylic acid with the amino group of pyrimidin-2-ylmethylamine. Used for treatment of erectile dysfunction.

References

• cas:330784-47-9
• drugcentral:4305
• kegg.drug:D03217
• patent:EP1366760
• patent:US6403597
• pubmed:18197727
• pubmed:18491987
• pubmed:20637970
• pubmed:20939743
• pubmed:21745238
• pubmed:21905762
• pubmed:22087063
• pubmed:22248153
• pubmed:22384456
• pubmed:22448738
• pubmed:22704456
• pubmed:22759639
• pubmed:22788525
• reaxys:11746013
• wikipedia.en:Avanafil

Ontology

ChEBI  ( EBI )