spiculoic acid A

Term ID

CHEBI:66520

Synonyms

(1R,3R,3aS,4S,5R,7aS)-3,4,5,7-tetraethyl-1-methyl-2-oxo-5-[(E)-2-phenylethenyl]-2,3,3a,4,5,7a-hexahydro-1H-indene-4-carboxylic acid

Definition

A carbobicyclic compound that is 2,3,3a,4,5,7a-hexahydro-1H-indene substituted by ethyl groups at positions 3, 4, 5 and 7, a methyl group at position 1, an oxo group at position 2, a 2-phenylethenyl group at position 5 and a carboxy group at position 4 (the 1R,3R,3aS,4S,5R,7aS stereoisomer). Isolated from Plakortis angulospiculatus, it exhibits cytotoxicity against human breast cancer MCF-7 cells.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: carbobicyclic compound cyclic ketone oxo monocarboxylic acid styrenes

carbobicyclic compound cyclic ketone oxo monocarboxylic acid styrenes Show first 5 Terms
has_role: antineoplastic agent metabolite

antineoplastic agent metabolite Show first 5 Terms

Phenotype

Phenotype resulting from spiculoic acid A

Phenotype where environments contain spiculoic acid A

Phenotype modified by environments containing spiculoic acid A

Human Disease / Model Data

Citations