TMC-89A

Term ID

CHEBI:66281

Synonyms

N-[(2R)-3-amino-2-methyl-3-oxopropanoyl]-L-threonyl-N-{1-[2-(hydroxymethyl)oxiran-2-yl]-4-methyl-1-oxopentan-2-yl}-L-threoninamide

Definition

An epoxide that is oxiran-2-ylmethanol which is acylated at position 2 by an N-[(2R)-3-amino-2-methyl-3-oxopropanoyl]-L-threonyl-L-threonylleucinyl group. It is a proteasome inhibitor isolated from Streptomyces sp. TC 1087.

References

PMID:11099231

Ontology

ChEBI ( EBI )

Relationships

is a type of: dicarboxylic acid diamide epoxide ketone primary alcohol secondary alcohol

dicarboxylic acid diamide epoxide ketone primary alcohol secondary alcohol Show first 5 Terms
has_role: antimicrobial agent bacterial metabolite proteasome inhibitor

antimicrobial agent bacterial metabolite proteasome inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from TMC-89A

Phenotype where environments contain TMC-89A

Phenotype modified by environments containing TMC-89A

Human Disease / Model Data

Citations