TMC-96

Term ID

CHEBI:66244

Synonyms

N-{1-[2-(hydroxymethyl)oxiran-2-yl]-4-methyl-1-oxopentan-2-yl}-N(2)-(3-methylbutanoyl)-L-threoninamide

Definition

An epoxide that is oxiran-2-ylmethanol which is acylated at position 2 by an N-(isovaleroyl)threonylleucinyl group. It is a proteasome inhibitor isolated from Saccharothrix.

References

PMID:10695669
PMID:10724010
Reaxys:8508507

Ontology

ChEBI ( EBI )

Relationships

is a type of: epoxide ketone monocarboxylic acid amide primary alcohol secondary alcohol

epoxide ketone monocarboxylic acid amide primary alcohol secondary alcohol Show first 5 Terms
has_role: antimicrobial agent antineoplastic agent bacterial metabolite proteasome inhibitor

antimicrobial agent antineoplastic agent bacterial metabolite proteasome inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from TMC-96

Phenotype where environments contain TMC-96

Phenotype modified by environments containing TMC-96

Human Disease / Model Data

Citations