salaspermic acid

Term ID

CHEBI:66153

Synonyms

• (3beta,20alpha)-3,24-epoxy-3-hydroxy-D:A-friedooleanan-29-oic acid
• (3S,5aR,7aS,7bR,9aS,12R,13aR,13bS,15aR,15bS,16R)-3-hydroxy-7b,9a,12,13b,15a,16-hexamethylicosahydro-3,5a-methanochryseno[2,1-c]oxepine-12(5H)-carboxylic acid

Definition

A hexacyclic triterpenoid that is D:A-friedooleanan-29-oic acid substituted by a hydroxy group at position 3 and an epoxy group across positions 3 and 24 (the (3β,20α stereoisomer). Isolated from Salacia macrosperma and Tripterygium wilfordii, it exhibits anti-HIV activity.

References

• cas:71247-78-4
• cba:338605
• cba:371262
• cba:379028
• pubmed:1375626
• pubmed:17972583
• pubmed:7720147
• pubmed:8158155
• reaxys:4889115

Ontology

ChEBI  ( EBI )

Resources

CTD