(2S)-(-)-kurarinone

Term ID

CHEBI:66150

Synonyms

(2S)-2-(2,4-dihydroxyphenyl)-7-hydroxy-5-methoxy-8-[(2R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl]-2,3-dihydro-4H-chromen-4-one
7,2',4'-trihydroxy-8-lavandulyl-5-methoxyflavanone

Definition

A trihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 7, 2' and 4', a lavandulyl group at position 8 and a methoxy group at position 5. Isolated from the roots of Sophora flavescens, it exhibits cytotoxicity against human myeloid leukemia HL-60 cells.

References

KEGG:C17446
LIPID_MAPS_instance:LMPK12140499
PMID:10843587
PMID:21831037
PMID:22932446
PMID:23333426
Patent:CN102018697
Patent:WO2005095375
Reaxys:9739392

Ontology

ChEBI ( EBI )

Relationships

is a type of: 4'-hydroxyflavanones monomethoxyflavanone trihydroxyflavanone

4'-hydroxyflavanones monomethoxyflavanone trihydroxyflavanone Show first 5 Terms
has_functional_parent: (2S)-flavanone

(2S)-flavanone Show first 5 Terms
has_role: antineoplastic agent metabolite

antineoplastic agent metabolite Show first 5 Terms
inverse has_functional_parent: (2S)-2'-methoxykurarinone

(2S)-2'-methoxykurarinone Show first 5 Terms

Phenotype

Phenotype resulting from (2S)-(-)-kurarinone

Phenotype where environments contain (2S)-(-)-kurarinone

Phenotype modified by environments containing (2S)-(-)-kurarinone

Human Disease / Model Data

Citations