hookerianamide J

Term ID

CHEBI:66022

Synonyms

(20S)-20-(N,N-dimethylamino)-3beta-(N-senecoylamino)-5alpha-preg-16-en-4beta-ol
N-[(3beta,4beta,5alpha,20S)-20-(dimethylamino)-4-hydroxypregn-16-en-3-yl]-3-methylbut-2-enamide

Definition

A steroid alkaloid that is 5alpha-preg-16-ene substituted by a hydroxy group at position 4, a N,N-dimethylamino group at position 20 and a N-senecoylamino group at position 3 (the 3beta,4beta,20S stereoisomer). Isolated from Sarcococca hookeriana, it exhibits antileishmanial and antibacterial activities.

References

PMID:18681480
Reaxys:18885924

Ontology

ChEBI ( EBI )

Relationships

is a type of: enamide secondary alcohol secondary carboxamide steroid alkaloid

enamide secondary alcohol secondary carboxamide steroid alkaloid Show first 5 Terms
has_functional_parent: 3-methylbut-2-enoic acid

3-methylbut-2-enoic acid Show first 5 Terms
has_parent_hydride: 5alpha-pregnane

5alpha-pregnane Show first 5 Terms
has_role: antibacterial agent antileishmanial agent EC 3.1.1.8 (cholinesterase) inhibitor plant metabolite

antibacterial agent antileishmanial agent EC 3.1.1.8 (cholinesterase) inhibitor plant metabolite Show first 5 Terms

Phenotype

Phenotype resulting from hookerianamide J

Phenotype where environments contain hookerianamide J

Phenotype modified by environments containing hookerianamide J

Human Disease Model