herquline B

Term ID

CHEBI:66012

Synonyms

(-)-herquline B
(1S,7S,8S,14S)-15-methyl-15,17-diazatetracyclo[12.2.2.1(3,7).1(8,12)]icosa-3(20),12(19)-diene-6,9-dione

Definition

An alkaloid comprising of a piperazine and cyclohexenone ring systems. Isolated from Penicillium herquei, it exhibits inhibitory activity against platelet aggregation.

References

CAS:174423-44-0
PMID:28278635
PMID:29085019
PMID:30561198
PMID:8609085
Reaxys:7436484

Ontology

ChEBI ( EBI )

Relationships

is a type of: alkaloid cyclic ketone organic heterotetracyclic compound secondary amino compound tertiary amino compound

alkaloid cyclic ketone organic heterotetracyclic compound secondary amino compound tertiary amino compound Show first 5 Terms
has_role: Penicillium metabolite platelet aggregation inhibitor

Penicillium metabolite platelet aggregation inhibitor Show first 5 Terms
inverse is_conjugate_acid_of: herquline B(1+)

herquline B(1+) Show first 5 Terms
is_conjugate_base_of: herquline B(1+)

herquline B(1+) Show first 5 Terms

Phenotype

Phenotype resulting from herquline B

Phenotype where environments contain herquline B

Phenotype modified by environments containing herquline B

Human Disease Model