fomitopinic acid A

Term ID

CHEBI:65902

Synonyms

(24S)-24,25-dihydroxy-3-oxolanost-8-en-21-oic acid

Definition

A tetracyclic triterpenoid that is lanost-8-ene substituted by hydroxy groups at positions 24 and 25 , a carboxylic acid at position 21 and an oxo grouo at position 3 (the 24S stereoisomer). Isolated from the fruit bodies of Fomitopsis pinicola, it exhibits antiinflammatory activity against cylooxygenase-1 (COX-1) and cylooxygenase-2 (COX-2).

References

PMID:15679320
Reaxys:10224261

Ontology

ChEBI ( EBI )

Relationships

is a type of: diol oxo monocarboxylic acid tetracyclic triterpenoid

diol oxo monocarboxylic acid tetracyclic triterpenoid Show first 5 Terms
has_parent_hydride: lanostane

lanostane Show first 5 Terms
has_role: cyclooxygenase 1 inhibitor cyclooxygenase 2 inhibitor metabolite

cyclooxygenase 1 inhibitor cyclooxygenase 2 inhibitor metabolite Show first 5 Terms

Phenotype

Phenotype resulting from fomitopinic acid A

Phenotype where environments contain fomitopinic acid A

Phenotype modified by environments containing fomitopinic acid A

Human Disease / Model Data

Citations