diuvaretin

Term ID

CHEBI:65802

Synonyms

1-[2,4-dihydroxy-3,5-bis(2-hydroxybenzyl)-6-methoxyphenyl]-3-phenylpropan-1-one

Definition

A member of the class of dihydrochalcones that is dihydrochalcone substituted by 2-hydroxybenzyl groups at positions 3 and 5, hydroxy groups at positions 2 and 4 and a methoxy group at position 6. Isolated from the roots of Uvaria acuminata and Uvaria chamae, it exhibits cytotoxicity towards human promyelocytic leukemia HL-60 cells.

References

lipidmaps:LMPK12120472
pubmed:12168763
pubmed:14709883
pubmed:15635168
pubmed:1775574
pubmed:845713
reaxys:2029684

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from diuvaretin

Phenotype where environments contain diuvaretin

Phenotype modified by environments containing diuvaretin

Phenotype affecting diuvaretin

Human Disease Model