cladoniamide G

Term ID

CHEBI:65639

Synonyms

(7R)-2,9-dichloro-7-hydroxy-13-methoxy-N-methyl-6-oxo-7,12-dihydro-6H-pyrido[1,2-a:3,4-b']diindole-7-carboxamide

Definition

An organic heteropentacyclic compound that is 7,12-dihydro-6H-pyrido[1,2-a:3,4-b']diindole substituted by chloro groups at positions 2 and 9, a hydroxy group at position 7, a methoxy group at position 13, a N-methyl carbamyl group at position 7 and an oxo group at position 6 (the 7R stereoisomer). It is isolated from the culture broth of Streptomyces uncialis and exhibits cytotoxicity against human breast cancer MCF- cells.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: cladoniamide lactam organic heteropentacyclic compound organochlorine compound secondary carboxamide ... Show All 6 Terms

cladoniamide lactam organic heteropentacyclic compound organochlorine compound secondary carboxamide tertiary alcohol Show first 5 Terms
has_role: antineoplastic agent

antineoplastic agent Show first 5 Terms

Phenotype

Phenotype resulting from cladoniamide G

Phenotype where environments contain cladoniamide G

Phenotype modified by environments containing cladoniamide G

Human Disease / Model Data

Citations