Search Ontology:
ChEBI

citrafungin A

Term ID
CHEBI:65635
Synonyms
  • 3-carboxy-2-O-[(3R)-3-carboxy-3-hydroxy-3-{(3R,5R)-2-oxo-5-[(1E,5Z)-tetradeca-1,5-dien-1-yl]tetrahydrofuran-3-yl}propanoyl]-3,4-dideoxy-L-threo-pentaric acid
Definition
A carboxylic ester obtained by the formal condensation of 4-carboxy group of (2R)-2-hydroxy-2-{(3R,5R)-2-oxo-5-[(1E,5Z)-tetradeca-1,5-dien-1-yl]tetrahydrofuran-3-yl}butanedioic acid with the hydroxy group of 3-carboxy-2,3-dideoxy-L-threo-pentaric acid. It is a fungal metabolite that acts as an inhibitor of geranylgeranyltransferase type I(GGTase I) of pathogenic fungal species.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
Phenotype
Phenotype resulting from citrafungin A
Phenotype where environments contain citrafungin A
Phenotype modified by environments containing citrafungin A
Human Disease Model