Search Ontology:
ChEBI
citrafungin A
- Term ID
- CHEBI:65635
- Synonyms
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- 3-carboxy-2-O-[(3R)-3-carboxy-3-hydroxy-3-{(3R,5R)-2-oxo-5-[(1E,5Z)-tetradeca-1,5-dien-1-yl]tetrahydrofuran-3-yl}propanoyl]-3,4-dideoxy-L-threo-pentaric acid
- Definition
- A carboxylic ester obtained by the formal condensation of 4-carboxy group of (2R)-2-hydroxy-2-{(3R,5R)-2-oxo-5-[(1E,5Z)-tetradeca-1,5-dien-1-yl]tetrahydrofuran-3-yl}butanedioic acid with the hydroxy group of 3-carboxy-2,3-dideoxy-L-threo-pentaric acid. It is a fungal metabolite that acts as an inhibitor of geranylgeranyltransferase type I(GGTase I) of pathogenic fungal species.
- References
-
- Chemspider:9585549
- PMID:14748587
- Reaxys:9682030
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_functional_parent
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- has_role
-
Phenotype
Phenotype resulting from citrafungin A
Phenotype where environments contain citrafungin A
Phenotype modified by environments containing citrafungin A
Human Disease Model