circumdatin H

Term ID

CHEBI:65634

Synonyms

(5bS)-2-methoxy-5b,6,7,8-tetrahydro-10H,16H-pyrrolo[2,1-c]quinazolino[3,2-a][1,4]benzodiazepine-10,16-dione
(S)-(-)-circumdatin H

Definition

An organic heteropentacyclic compound that is 5b,7,8,16-tetrahydro-6H,10H-pyrrolo[2,1-c]quinazolino[3,2-a][1,4]benzodiazepine substituted by a methoxy group at position 2 and oxo groups at positions 10 and 16 (the 5bS stereoisomer). An alkaloid isolated from the culture broth of Aspergillus ochraceus, it exhibits potent inhibitory activity towards mitochondrial NADH oxidase.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: alkaloid aromatic ether lactam organic heteropentacyclic compound

alkaloid aromatic ether lactam organic heteropentacyclic compound Show first 5 Terms
has_role: Aspergillus metabolite EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor metabolite

Aspergillus metabolite EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor metabolite Show first 5 Terms

Phenotype

Phenotype resulting from circumdatin H

Phenotype where environments contain circumdatin H

Phenotype modified by environments containing circumdatin H

Human Disease / Model Data

Citations