cathestatin A

Term ID

CHEBI:65599

Synonyms

(2S,3S)-3-({(2S)-1-[(4-aminobutyl)amino]-1-oxo-3-phenylpropan-2-yl}carbamoyl)oxirane-2-carboxylic acid

Definition

A dicarboxylic acid monoamide obtained by the formal condensation of the carboxylic group of oxirane-2,3-dicarboxylic acid with the amino group of N-(4-aminobutyl)-L-phenylalaninamide (the 2S,3S stereoisomer). An antibiotic isolated from the fermentation broth of Penicillium citrinum, it acts as a potent inhibitor of cysteine protease.

References

Chemspider:8103948
PMID:7766039
PMID:8642005
Reaxys:7229726

Ontology

ChEBI ( EBI )

Relationships

is a type of: dicarboxylic acid monoamide epoxide monocarboxylic acid primary amino compound

dicarboxylic acid monoamide epoxide monocarboxylic acid primary amino compound Show first 5 Terms
has_role: antimicrobial agent cysteine protease inhibitor Penicillium metabolite

antimicrobial agent cysteine protease inhibitor Penicillium metabolite Show first 5 Terms

Phenotype

Phenotype resulting from cathestatin A

Phenotype where environments contain cathestatin A

Phenotype modified by environments containing cathestatin A

Human Disease / Model Data

Citations