Search Ontology:
ChEBI

calotropone

Term ID
CHEBI:65568
Synonyms
  • (3beta,12beta,14beta,17alpha)-3,14,17-trihydroxy-20-oxopregn-5-en-12-yl benzoate
  • 12beta-benzoyloxy-3beta,14beta,17beta-trihydroxypregnane-20-one
  • 12beta-O-benzoyl-3beta,14beta,17beta-trihydroxypregnane-20-one
  • 3beta,14beta,17-trihydroxy-20-oxo-17alpha-pregn-5-en-12beta-yl benzoate
Definition
A 20-oxo steroid that is 17alpha-pregn-5-en-20-one substituted by a benzoyloxy group at position 12 and hydroxy groups at positions 3, 14 and 17 (the 3beta,12beta,14beta stereoisomer). It is isolated from the roots of Calotropis gigantea and displays inhibitory effects towards chronic myelogenous leukemia K562 and human gastric cancer SGC-7901 cell lines.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_parent_hydride
has_role
Phenotype
Phenotype resulting from calotropone
Phenotype where environments contain calotropone
Phenotype modified by environments containing calotropone
Human Disease Model
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