asprellic acid A

Term ID

CHEBI:65455

Synonyms

(3beta)-3,27-bis{[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}olean-12-en-28-oic acid
3,27-di-O-trans-p-coumaroyl-3beta,27-dihydroxy-olean-12-en-28-oic acid

Definition

A pentacyclic triterpenoid that is the diester obtained by the global condensation of the hydroxy groups of (3beta)-3,27-dihydroxyolean-12-en-28-oic acid with trans-4-coumaric acid. It is isolated from the dried leaves of Ilex asprella and exhibits significant toxicity against KB (epidermoid carcinoma of the nasopharynx) and RPMI-7951 (melanoma) cell lines.

References

CAS:152509-92-7
PMID:8133297

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: diester monocarboxylic acid pentacyclic triterpenoid

diester monocarboxylic acid pentacyclic triterpenoid Show first 5 Terms
has_functional_parent: (3beta)-3,27-dihydroxyolean-12-en-28-oic acid trans-4-coumaric acid

(3beta)-3,27-dihydroxyolean-12-en-28-oic acid trans-4-coumaric acid Show first 5 Terms
has_role: antineoplastic agent metabolite

antineoplastic agent metabolite Show first 5 Terms

Phenotype

Phenotype resulting from asprellic acid A

Phenotype where environments contain asprellic acid A

Phenotype modified by environments containing asprellic acid A

Human Disease Model