andrographolide

Term ID

CHEBI:65408

Synonyms

• (1R-(1-alpha(E(S)),4abeta,5alpha,6alpha,8aalpha))-3-(2-(decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl)ethylidene)dihydro-4-hydroxy-2(3H)-furanone
• (3E,4S)-4-hydroxy-3-{2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidenedecahydronaphthalen-1-yl]ethylidene}dihydrofuran-2(3H)-one
• 3-(2-(decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenenaphthyl)ethylidene)dihydro-4-hydroxyfuran-2(3H)-one
• 3alpha,14,15,18-tetrahydroxy-5b,9bH,10a-labda-8(20),12-dien-16-oic acid gamma-Lactone

Definition

A labdane diterpenoid isolated from the leaves and roots of Andrographis paniculata that exhibits anti-HIV, anti-inflammatory and antineoplastic properties.

References

• cas:5508-58-7
• kegg.compound:C20214
• patent:CN102397273
• patent:EP2411004
• pubmed:15894448
• pubmed:18464090
• pubmed:19110075
• pubmed:22026410
• pubmed:22512591
• pubmed:22858223
• reaxys:5609598
• wikipedia.en:Andrographolide

Ontology

ChEBI  ( EBI )

Resources

CTD