Search Ontology:
ChEBI
ageladine A
- Term ID
- CHEBI:65373
- Synonyms
-
- 4-(4,5-dibromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine
- Definition
- An imidazopyridine that is 1H-imidazo[4,5-c]pyridin-2-amine substituted by a 4,5-dibromo-1H-pyrrol-2-yl group at position 4. It is an alkaloid isolated from a marine sponge Agelas nakamurai and acts as an inhibitor of the matrix metalloproteinases, the key enzymes involved in tumour growth, migration, angiogenesis, invasion and metastasis.
- References
-
- PMID:14677933
- PMID:16562912
- PMID:17261003
- PMID:19948404
- PMID:22363232
- Patent:WO2009152584
- Reaxys:9568941
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from ageladine A
Phenotype where environments contain ageladine A
Phenotype modified by environments containing ageladine A
Human Disease Model