Search Ontology:
ChEBI

alvespimycin

Term ID
CHEBI:65324
Synonyms
  • (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-{[2-(dimethylamino)ethyl]amino}-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
  • 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin
  • 17-DMAG
Definition
A 19-membered macrocyle that is geldanamycin in which the methoxy group attached to the benzoquinone moiety has been replaced by a 2-(N,N-dimethylamino)ethylamino group.
References
  • cas:467214-20-6
  • drugbank:DB03080
  • pdb-ccd:KOS
  • pubmed:19371599
  • pubmed:21278242
  • pubmed:21663398
  • pubmed:21718076
  • pubmed:22547655
  • pubmed:22694478
  • pubmed:23635099
  • pubmed:23843639
  • pubmed:24293393
  • pubmed:24304935
  • pubmed:24471734
  • reaxys:9890433
  • wikipedia.en:17-Dimethylaminoethylamino-17-demethoxygeldanamycin
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from alvespimycin
Phenotype where environments contain alvespimycin
Phenotype modified by environments containing alvespimycin
Phenotype affecting alvespimycin
Human Disease Model