Search Ontology:
ChEBI
lomustine
- Term ID
- CHEBI:6520
- Synonyms
-
- 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea
- 1-(2-chloroethyl)-3-cyclohexylnitrosourea
- Belustine
- CCNU
- Cecenu
- CeeNU
- chloroethylcyclohexylnitrosourea
- CINU
- cyclohexyl chloroethyl nitrosourea
- lomustina
- lomustine
- lomustinum
- N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea
- Definition
- An N-nitrosourea that is urea in which one of the nitrogens is substituted by a 2-chloroethyl group and by a nitroso group, while the other nitrogen is substituted by a cyclohexyl group. An alkylating antineoplastic agent, it is used in the treatment of brain tumours, lung cancer, malignant melanoma and other solid tumours.
- References
-
- cas:13010-47-4
- drugbank:DB01206
- drugcentral:1596
- hmdb:HMDB0015337
- kegg.compound:C07079
- kegg.drug:D00363
- pubmed:12153595
- pubmed:19901016
- pubmed:20719460
- pubmed:22577051
- pubmed:24293673
- pubmed:24368412
- pubmed:24516018
- pubmed:6762924
- reaxys:2125058
- wikipedia.en:Lomustine
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
Phenotype
Phenotype resulting from lomustine
Phenotype where environments contain lomustine
Phenotype modified by environments containing lomustine
Phenotype affecting lomustine
Human Disease Model