F-9775B

Term ID

CHEBI:64409

Synonyms

1,7-dihydroxy-3,8a,11,11b-tetramethyl-11a,11b-dihydrobenzo[b]cyclopenta[2,3]indeno[4,5-e][1,4]dioxine-6,8,9(8aH)-trione

Definition

An organic heteropentacyclic compound and polyketide that is 11a,11b-dihydrobenzo[b]cyclopenta[2,3]indeno[4,5-e][1,4]dioxine-6,8,9(8aH)-trione which is substituted by hydroxy groups at positions 1 and 7, and by methyl groups at the 3, 8a, 11 and 11b positions. A cathepsin K inhibitor, it was first isolated from Paecilomyces carneus and subsequently obtained from Aspergillus nidulans cocultivated with a soil-dwelling actinomycete.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: organic heteropentacyclic compound phenols polyketide

organic heteropentacyclic compound phenols polyketide Show first 5 Terms
has_role: EC 3.4.22.38 (cathepsin K) inhibitor fungal metabolite

EC 3.4.22.38 (cathepsin K) inhibitor fungal metabolite Show first 5 Terms

Phenotype

Phenotype resulting from F-9775B

Phenotype where environments contain F-9775B

Phenotype modified by environments containing F-9775B

Human Disease Model