Search Ontology:
ChEBI

pregabalin

Term ID
CHEBI:64356
Synonyms
  • (3S)-3-(aminomethyl)-5-methylhexanoic acid
  • (S)-3-Isobutyl GABA
  • 3-Isobutyl GABA
  • Lyrica
  • pregabalin
Definition
A gamma-amino acid that is gamma-aminobutyric acid (GABA) carrying an isobutyl substitutent at the beta-position (the S-enantiomer). Binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
Phenotype
Phenotype resulting from pregabalin
Phenotype where environments contain pregabalin
Phenotype modified by environments containing pregabalin
Human Disease Model
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.