Search Ontology:
ChEBI
pregabalin
- Term ID
- CHEBI:64356
- Synonyms
-
- (3S)-3-(aminomethyl)-5-methylhexanoic acid
- (S)-3-Isobutyl GABA
- 3-Isobutyl GABA
- Lyrica
- pregabalin
- Definition
- A γ-amino acid that is γ-aminobutyric acid (GABA) carrying an isobutyl substitutent at the β-position (the S-enantiomer). Binds with high affinity to the α2-δ site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues.
- References
-
- cas:148553-50-8
- drugbank:DB00230
- drugcentral:2255
- kegg.drug:D02716
- patent:EP1178034
- patent:EP2418194
- patent:US2008311635
- patent:US6359169
- pubmed:22339078
- pubmed:22345870
- pubmed:22362672
- pubmed:22366121
- pubmed:22404404
- pubmed:22413436
- pubmed:22415534
- pubmed:22415535
- pubmed:22424859
- pubmed:22431439
- pubmed:22448469
- pubmed:22449111
- pubmed:22459341
- pubmed:22468635
- pubmed:22470326
- pubmed:22473300
- pubmed:22473872
- pubmed:22476240
- pubmed:22480279
- reaxys:8404778
- wikipedia.en:Pregabalin
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from pregabalin
Phenotype where environments contain pregabalin
Phenotype modified by environments containing pregabalin
Phenotype affecting pregabalin
Human Disease Model