Search Ontology:
ChEBI

memantine hydrochloride

Term ID
CHEBI:64323
Synonyms
  • 1-Amino-3,5-dimethyladamantane hydrochloride
  • 3,5-Dimethyl-1-adamantanamine hydrochloride
  • 3,5-dimethyladamantan-1-amine hydrochloride
  • 3,5-dimethyladamantan-1-aminium chloride
  • 3,5-dimethyltricyclo(3.3.1.1(3,7))decan-1-amine hydrochloride
  • Memantine HCl
  • memantine.HCl
  • Namenda
Definition
A hydrochloride obtained by reaction of memantine with one equivalent of hydrochloric acid. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.
References
  • cas:41100-52-1
  • drugbank:DB01043
  • kegg.drug:D04905
  • patent:US2011282100
  • patent:WO2011125062
  • pubmed:19196860
  • pubmed:20013176
  • pubmed:20703320
  • pubmed:20926740
  • pubmed:21213317
  • pubmed:21220675
  • pubmed:21268245
  • pubmed:21792308
  • pubmed:21875407
  • pubmed:21893967
  • pubmed:22214393
  • reaxys:6573843
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from memantine hydrochloride
Phenotype where environments contain memantine hydrochloride
Phenotype modified by environments containing memantine hydrochloride
Phenotype affecting memantine hydrochloride
Human Disease Model