Search Ontology:
ChEBI

crizotinib

Term ID
CHEBI:64310
Synonyms
  • (R)-crizotinib
  • 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine
  • crizotinib
  • crizotinibum
  • PF 2341066
  • PF-2341066
Definition
A 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine that has R configuration at the chiral centre. The active enantiomer, it acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC)
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
inverse has_part
inverse is_enantiomer_of
is_enantiomer_of
Phenotype
Phenotype resulting from crizotinib
Phenotype where environments contain crizotinib
Phenotype modified by environments containing crizotinib
Human Disease / Model Data
Citations
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