8-Br-cAMP

Term ID

CHEBI:64211

Synonyms

(4aR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide
8-bromo cyclic adenosine monophosphate
8-bromo-cAMP
8-bromo-cyclic 3',5'-AMP
8-bromo-cyclic AMP
8-bromoadenosine 3',5'-(hydrogen phosphate)
8-bromoadenosine 3',5'-cyclic monophosphate
8-bromoadenosine 3',5'-monophosphate
8-bromoadenosine cyclic 3',5'-phosphate
BCAMP
cyclic 8-bromoadenosine 3',5'-monophosphate

Definition

A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic AMP bearing an additional bromo substituent at position 8 on the adenine ring. An activator of cyclic AMP-dependent protein kinase, but resistant to degradation by cyclic AMP phosphodiesterase.

References

cas:23583-48-4
pubmed:10543424
pubmed:10708595
pubmed:11906532
pubmed:12216111
pubmed:1320750
pubmed:1367038
pubmed:15121638
pubmed:15169861
pubmed:15225757
pubmed:15717604
pubmed:16134057
pubmed:16214133
pubmed:16425431
pubmed:17140607
pubmed:18239846
pubmed:1849229
pubmed:19121393
pubmed:1982459
pubmed:19833172
pubmed:21120637
pubmed:21284604
pubmed:2240104
pubmed:2413029
pubmed:24493289
pubmed:24518258
pubmed:24605759
pubmed:2478258
pubmed:2560108
pubmed:2581952
pubmed:2744214
pubmed:29887570
pubmed:29997437
pubmed:3032362
pubmed:30374127
pubmed:3094467
pubmed:6128338
pubmed:6196214
pubmed:6327153
pubmed:6367831
pubmed:7996791
pubmed:8095554
pubmed:8107042
pubmed:8394699
pubmed:8699249
pubmed:8730238
pubmed:8841091
pubmed:9042334
pubmed:9327456
pubmed:9713380
reaxys:591930
wikipedia.en:8-Bromoadenosine_3',5'-cyclic_monophosphate

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from 8-Br-cAMP

Phenotype where environments contain 8-Br-cAMP

Phenotype modified by environments containing 8-Br-cAMP

Phenotype affecting 8-Br-cAMP

Human Disease Model