Search Ontology:
ChEBI

carmoxirole

Term ID
CHEBI:64200
Synonyms
  • 3-(4-(3,6-Dihydro-4-phenyl-1(2H)-pyridyl)butyl)indole-5-carboxylic acid
  • 3-[4-(4-phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indole-5-carboxylic acid
  • carmoxirol
  • carmoxirole
  • carmoxirolum
Definition
An indolecarboxylic acid that is indole-5-carboxylic acid bearing an additional 4-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)butyl substituent at position 3. Selective, peripherally acting dopamine D2 receptor agonist. Modulates noradrenalin release and sympathetic activation. Displays antihypertensive properties in vivo.
References
  • cas:98323-83-2
  • lincs.smallmolecule:LSM-3850
  • patent:DE3342632
  • patent:EP0548635
  • patent:US5256673
  • pubmed:10099036
  • pubmed:12106810
  • pubmed:1352381
  • pubmed:1356782
  • pubmed:1356783
  • pubmed:15109678
  • pubmed:1682817
  • pubmed:22051191
  • pubmed:7757314
  • pubmed:7902890
  • pubmed:8097997
  • pubmed:9825185
  • reaxys:5772553
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from carmoxirole
Phenotype where environments contain carmoxirole
Phenotype modified by environments containing carmoxirole
Phenotype affecting carmoxirole
Human Disease Model