Search Ontology:
ChEBI

clobenpropit

Term ID
CHEBI:64177
Synonyms
  • 3-(1H-imidazol-4-yl)propyl N-(4-chlorobenzyl)carbamimidothioate
  • S-(3-(4(5)-Imidazolyl))propyl-N-(4-chlorobenzyl)isothiourea
Definition
An imidothiocarbamic ester that consists of isothiourea bearing S-3-(imidazol-4-yl)propyl and N-4-chlorobenzyl substituents. An extremely potent histamine H3 antagonist/inverse agonist (pA2 = 9.93). Also displays partial agonist activity at H4 receptors; induces eosinophil shape change with an EC50 of 3 nM.
References
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from clobenpropit
Phenotype where environments contain clobenpropit
Phenotype modified by environments containing clobenpropit
Phenotype affecting clobenpropit
Human Disease Model
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