5-nonyloxytryptamine

Term ID

CHEBI:64149

Synonyms

2-[5-(nonyloxy)-1H-indol-3-yl]ethanamine
3-(2-aminoethyl)-5-nonyloxyindole
5-(Nonyloxy)-1H-indole-3-ethanamine
5-(Nonyloxy)tryptamine
O-nonylserotonin

Definition

A tryptamine derivative that consists of serotonin bearing an additional O-nonyl substituent. 5-HT1B selective agonist, several times more potent than sumatriptan and inactive as a 5-HT1A agonist (Ki at 5-HT1B = 1 nM, selectivity over 5-HT1A > 300-fold).

References

CAS:157798-12-4
LINCS:LSM-20005
Patent:US5496957
Reaxys:7077925

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: aromatic ether primary amino compound tryptamines

aromatic ether primary amino compound tryptamines Show first 5 Terms
has_functional_parent: serotonin

serotonin Show first 5 Terms
has_role: serotonergic agonist

serotonergic agonist Show first 5 Terms
inverse is_conjugate_acid_of: 5-nonyloxytryptaminium(1+)

5-nonyloxytryptaminium(1+) Show first 5 Terms
is_conjugate_base_of: 5-nonyloxytryptaminium(1+)

5-nonyloxytryptaminium(1+) Show first 5 Terms

Phenotype

Phenotype resulting from 5-nonyloxytryptamine

Phenotype where environments contain 5-nonyloxytryptamine

Phenotype modified by environments containing 5-nonyloxytryptamine

Human Disease / Model Data

Citations