(S)-(-)-sulpiride

Term ID

CHEBI:64119

Synonyms

• (-)-N-(((S)-1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide
• (-)-sulpiride
• (S)-(-)-5-aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide
• (S)-(-)-N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide
• (S)-sulpiride
• levosulpirida
• levosulpiride
• levosulpiridum
• N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-2-methoxy-5-sulfamoylbenzamide
• S-(-)-N-(1-Ethyl-2-pyrrolidinomethyl)-2-methoxy-5-sulfamoylebenzamide

Definition

An optically active form of sulpiride having (S)-configuration. The active enantiomer of the racemic drug sulpiride. Selective D2-like dopamine antagonist (Ki values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 muM at D2, D3, D4, D1 and D5 receptors respectively).

References

• CAS:23672-07-3
• DrugBank:DB00391
• Drug_Central:1577
• KEGG:D07312
• LINCS:LSM-5624
• PMID:18186115
• PMID:19165957
• PMID:19452563
• PMID:19488984
• PMID:19795476
• PMID:20438811
• PMID:20656570
• PMID:20850200
• PMID:21223496
• PMID:21615988
• Patent:KR20110090142
• Patent:US2011052700
• Reaxys:3563418
• Wikipedia:Levosulpiride

Ontology

ChEBI  ( EBI )

Resources

CTD