artesunate

Term ID

CHEBI:63918

Synonyms

• 4-oxo-4-{[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10-yl]oxy}butanoic acid
• artesunate
• artesunato
• artesunatum
• artesunic acid
• AS
• butanedioic acid, 1-[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester
• dihydroqinghasu hemsuccinate

Definition

An artemisinin derivative that is the hemisuccinate ester of the lactol resulting from the reduction of the lactone carbonyl group of artemisinin. It is used, generally as the sodium salt, for the treatment of malaria.

References

• CAS:182824-33-5
• CAS:88495-63-0
• Chemspider:5293084
• DrugBank:DB09274
• Drug_Central:247
• HMDB:HMDB0240267
• KEGG:D02482
• PDBeChem:D95
• PMID:26097885
• PMID:30704910
• PMID:33652561
• PMID:33792170
• PMID:33814617
• PMID:33920029
• Reaxys:6003212
• Wikipedia:Artesunate

Ontology

ChEBI  ( EBI )

Resources

CTD