Search Ontology:
ChEBI

iloprost

Term ID
CHEBI:63916
Synonyms
  • (16R,S)-methyl-18,18,19,19-tetradehydro-6a-carbaprostaglandin I2
  • (5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]hexahydropentalen-2(1H)-ylidene]pentanoic acid
  • iloprost
  • iloprostum
Definition
A carbobicyclic compound that is prostaglandin I2 in which the endocyclic oxygen is replaced by a methylene group and in which the (1E,3S)-3-hydroxyoct-1-en-1-yl side chain is replaced by a (3R)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl group. A synthetic analogue of prostacyclin, it is used as the trometamol salt (generally by intravenous infusion) for the treatment of peripheral vascular disease and pulmonary hypertension.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from iloprost
Phenotype where environments contain iloprost
Phenotype modified by environments containing iloprost
Human Disease / Model Data
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