lenalidomide

Term ID

CHEBI:63791

Synonyms

• 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline
• 3-(4-amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione
• 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione
• lenalidomide
• Revlimid

Definition

A dicarboximide that consists of 1-oxoisoindoline bearing an amino substituent at position 4 and a 2,6-dioxopiperidin-3-yl group at position 2. Inhibits the secretion of TNF-α.

References

• cas:191732-72-6
• drugbank:DB00480
• drugcentral:3317
• kegg.drug:D04687
• lincs.smallmolecule:LSM-6187
• pubmed:21533608
• pubmed:21823830
• pubmed:21835953
• pubmed:22001752
• pubmed:22066855
• pubmed:22107129
• pubmed:22143062
• pubmed:22211836
• pubmed:22241792
• pubmed:22245427
• pubmed:22245805
• pubmed:22245806
• pubmed:22246035
• pubmed:22253550
• pubmed:22261445
• reaxys:8335210
• wikipedia.en:Lenalidomide

Ontology

ChEBI  ( EBI )

Resources

CTD