lapachol

Term ID

CHEBI:6377

Synonyms

• 2-hydroxy-3-(3-methyl-2-buten-1-yl)-1,4-naphthalenedione
• 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthalenedione
• 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone
• 2-hydroxy-3-(3-methylbut-2-en-1-yl)-1,4-dihydronaphthalene-1,4-dione
• 2-hydroxy-3-(3-methylbut-2-en-1-yl)naphthalene-1,4-dione
• Bethabarra wood
• C.I. 75490
• C.I. natural yellow 16
• greenhartin
• Ipe-tobacco wood
• Lapachol
• lapachol wood
• Surinam greenheart wood
• Taigu wood
• taiguic acid
• tecomin

Definition

A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone substituted by hydroxy and 3-methylbut-2-en-1-yl groups at positions 2 and 3, respectively. It is a natural compound that exhibits antibacterial and anticancer properties, first isolated in 1882 from the bark of Tabebuia avellanedae.

References

• cas:84-79-7
• chemspider:10770962
• hmdb:HMDB0253978
• kegg.compound:C10366
• knapsack:C00002835
• pubmed:11180522
• pubmed:30797783
• pubmed:30896339
• pubmed:31183610
• pubmed:31935485
• pubmed:32318101
• pubmed:32712193
• pubmed:33019942
• pubmed:33254016
• pubmed:33275860
• wikipedia.en:Lapachol

Ontology

ChEBI  ( EBI )

Resources

CTD