Search Ontology:
ChEBI
tenofovir disoproxil
- Term ID
- CHEBI:63717
- Synonyms
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- 9-((R)-2-((bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine
- bis(POC)PMPA
- bis({[(propan-2-yloxy)carbonyl]oxy}methyl) ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate
- PMPA prodrug
- tenofovir bis(isopropyloxycarbonyloxymethyl) ester
- Definition
- An organic phosphonate that is the disoproxil ester of tenofovir. A prodrug for tenofovir, an HIV-1 reverse transcriptase inhibitor, tenofovir disoproxil is used as the fumaric acid salt in combination therapy for the treatment of HIV infection.
- References
-
- CAS:201341-05-1
- DrugBank:DB00300
- Drug_Central:2593
- Patent:WO5922695
- Patent:WO9804569
- Reaxys:9018187
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_functional_parent
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- has_role
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- inverse has_part
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Phenotype
Phenotype resulting from tenofovir disoproxil
Phenotype where environments contain tenofovir disoproxil
Phenotype modified by environments containing tenofovir disoproxil
Human Disease Model