topiramate

Term ID

CHEBI:63631

Synonyms

• 2,3:4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
• 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose sulfamate
• McN-4853
• RWJ-17021
• tipiramate
• tipiramato
• Topamax
• topiramate
• topiramato
• topiramatum
• TPM

Definition

A hexose derivative that is 2,3:4,5-di-O-isopropylidene-β-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine.

References

• cas:97240-79-4
• drugbank:DB00273
• drugcentral:2706
• kegg.compound:C07502
• kegg.drug:D00537
• lincs.smallmolecule:LSM-5435
• patent:US4513006
• pdb-ccd:TOR
• pubmed:22233396
• pubmed:22249827
• reaxys:5988957
• wikipedia.en:Topiramate

Ontology

ChEBI  ( EBI )

Resources

CTD