Search Ontology:
ChEBI
tolcapone
- Term ID
- CHEBI:63630
- Synonyms
-
- (3,4-dihydroxy-5-nitrophenyl)(4-methylphenyl)methanone
- 3,4-Dihydroxy-4'-methyl-5-nitrobenzophenone
- 3,4-dihydroxy-5-nitro-4'-methylbenzophenone
- 4'-methyl-3,4-dihydroxy-5-nitrobenzophenone
- tolcapone
- Definition
- Benzophenone substituted on one of the phenyl rings at C-3 and C-4 by hydroxy groups and at C-5 by a nitro group, and on the other phenyl ring by a methyl group at C-4. It is an inhibitor of catechol O-methyltransferase.
- References
-
- drugbank:DB00323
- drugcentral:2697
- kegg.drug:D00786
- lincs.smallmolecule:LSM-5282
- patent:EP237929
- patent:US5236952
- pubmed:20381177
- pubmed:20502133
- pubmed:21521027
- pubmed:22136163
- reaxys:8151577
- wikipedia.en:Tolcapone
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from tolcapone
Phenotype where environments contain tolcapone
Phenotype modified by environments containing tolcapone
Phenotype affecting tolcapone
Human Disease Model