Search Ontology:
ChEBI
misoprostol
- Term ID
- CHEBI:63610
- Synonyms
-
- (+-)-methyl (1R,2R,3R)-3-hydroxy-2-((E)-(4RS)-4-hydroxy-4-methyl-1-octenyl)-5-oxocyclopentaneheptanoate
- (11-alpha,13E)-(+-)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid methyl ester
- Arthrotec
- Cytotec
- Methyl (+-)-11-alpha,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate
- misoprostol
- misoprostolum
- Definition
- A diastereoisomeric mixture composed of approximately equal amounts of a double racemate of four of the sixteen possible diastereoisomers of methyl (13E)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate that is racemic prostaglandin E1 which is lacking the hydroxy group at position 15, but which has an additional hydroxy group at position 16. It is a synthetic prostaglandin E1 analogue, used in the treatment of gastric and duodenal ulcers. A weak abortifacient, it is also used for cervical ripening prior to surgical termination of pregnancy. The (11R,16S)-diastereoisomer is the pharmacologically active form.
- References
-
- CAS:59122-46-2
- DrugBank:DB00929
- KEGG:D00419
- PMID:10945193
- PMID:10949752
- PMID:11136959
- PMID:1417145
- PMID:18690850
- PMID:19740175
- PMID:2109814
- PMID:3080288
- Patent:BE827127
- Patent:US3965143
- Reaxys:4155643
- Wikipedia:Misoprostol
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_part
-
- has_role
-
Phenotype
Phenotype resulting from misoprostol
Phenotype where environments contain misoprostol
Phenotype modified by environments containing misoprostol
Human Disease Model