Search Ontology:
ChEBI
leuprolide acetate
- Term ID
- CHEBI:63597
- Synonyms
-
- 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tryosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide monoacetate
- 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide--acetic acid (1/1)
- Enantone
- Leuprorelin acetate
- Lupron
- Lutrate
- Pyr-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt.HOAc
- Definition
- An acetate salt obtained by combining the nonapeptide leuprolide with acetic acid. A long lasting GnRH analog, LH-Rh agonist. It is a synthetic nonapeptide analogue of gonadotropin-releasing hormone, and is used as a subcutaneous hydrogel implant for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty.
- References
-
- cas:74381-53-6
- drugbank:DB00007
- kegg.drug:D00989
- pubmed:21239017
- pubmed:21276459
- pubmed:21324455
- pubmed:21564386
- pubmed:21790701
- pubmed:21801354
- pubmed:21847353
- pubmed:21860633
- pubmed:21864378
- pubmed:22025196
- pubmed:22050405
- pubmed:22133574
- pubmed:22136615
- reaxys:5570787
- wikipedia.en:Leuprorelin
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from leuprolide acetate
Phenotype where environments contain leuprolide acetate
Phenotype modified by environments containing leuprolide acetate
Phenotype affecting leuprolide acetate
Human Disease Model