leuprolide acetate

Term ID

CHEBI:63597

Synonyms

5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tryosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide monoacetate
5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide--acetic acid (1/1)
Enantone
Leuprorelin acetate
Lupron
Lutrate
Pyr-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt.HOAc

Definition

An acetate salt obtained by combining the nonapeptide leuprolide with acetic acid. A long lasting GnRH analog, LH-Rh agonist. It is a synthetic nonapeptide analogue of gonadotropin-releasing hormone, and is used as a subcutaneous hydrogel implant for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: acetate salt

acetate salt Show first 5 Terms
has_part: leuprolide

leuprolide Show first 5 Terms
has_role: antineoplastic agent gonadotropin releasing hormone agonist

antineoplastic agent gonadotropin releasing hormone agonist Show first 5 Terms

Phenotype

Phenotype resulting from leuprolide acetate

Phenotype where environments contain leuprolide acetate

Phenotype modified by environments containing leuprolide acetate

Human Disease / Model Data

Citations