Search Ontology:
ChEBI
etravirine
- Term ID
- CHEBI:63589
- Synonyms
-
- 4-({6-amino-5-bromo-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile
- etravirine
- Definition
- An aminopyrimidine that consists of 2,6-diaminopyrimidine bearing a bromo substituent at position 5, a 4-cyano-2,6-dimethylphenoxy substituent at position 4 and having a 4-cyanophenyl substituent attached to the 2-amino group. NNRTI of HIV-1, binds directly to RT and blocks RNA-dependent and DNA-dependent DNA polymerase activities
- References
-
- CAS:269055-15-4
- DrugBank:DB06414
- KEGG:D04112
- PMID:21114458
- PMID:21142266
- PMID:21173188
- PMID:21189339
- PMID:21383098
- PMID:21464253
- PMID:21557669
- PMID:21600016
- PMID:21637112
- PMID:21881478
- PMID:22011983
- PMID:22089378
- PMID:22190606
- PMID:25017682
- Reaxys:8945855
- Wikipedia:Etravirine
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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Phenotype
Phenotype resulting from etravirine
Phenotype where environments contain etravirine
Phenotype modified by environments containing etravirine
Human Disease Model