Search Ontology:
ChEBI
cabazitaxel
- Term ID
- CHEBI:63584
- Synonyms
-
- (2alpha,5beta,7beta,10beta,13alpha)-4-acetoxy-13-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1-hydroxy-7,10-dimethoxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
- cabazitaxel
- cabazitaxelum
- Definition
- A tetracyclic diterpenoid that is 10-deacetylbaccatin III having O-methyl groups attached at positions 7 and 10 as well as an O-(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl group attached at position 13. Acts as a microtubule inhibitor, binds tubulin and promotes microtubule assembly and simultaneously inhibits disassembly.
- References
-
- cas:183133-96-2
- drugbank:DB06772
- drugcentral:4153
- kegg.drug:D09755
- pubmed:21174534
- pubmed:21339064
- pubmed:21406025
- pubmed:21448449
- pubmed:21455038
- pubmed:21461278
- pubmed:21463139
- pubmed:21695098
- pubmed:21734586
- pubmed:21748753
- pubmed:21770474
- pubmed:22048000
- pubmed:22079047
- pubmed:22111007
- pubmed:22229405
- reaxys:14351224
- wikipedia.en:Cabazitaxel
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from cabazitaxel
Phenotype where environments contain cabazitaxel
Phenotype modified by environments containing cabazitaxel
Phenotype affecting cabazitaxel
Human Disease Model