Search Ontology:
ChEBI
lamivudine
- Term ID
- CHEBI:63577
- Synonyms
-
- (-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
- (-)-2'-Deoxy-3'-thiacytidine
- 2',3'-Dideoxy-3'-thiacytidine
- 3'-Thia-2',3'-dideoxycytidine
- 3TC
- 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
- beta-L-2',3'-Dideoxy-3'-thiacytidine
- beta-L-3'-Thia-2',3'-dideoxycytidine
- Epivir
- lamivudine
- Definition
- A monothioacetal that consists of cytosine having a (2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl moiety attached at position 1. An inhibitor of HIV-1 reverse transcriptase, it is used as an antiviral in the treatment of AIDS and hepatitis B.
- References
-
- cas:134678-17-4
- drugbank:DB00709
- drugcentral:1539
- kegg.compound:C07065
- kegg.drug:D00353
- lincs.smallmolecule:LSM-5215
- patent:WO9117159
- pdb-ccd:3TC
- pubmed:12135009
- pubmed:19783232
- pubmed:21465499
- pubmed:21721935
- pubmed:21851334
- pubmed:22001270
- pubmed:22028068
- pubmed:22078148
- pubmed:22085635
- pubmed:22097898
- pubmed:22098177
- pubmed:22170540
- pubmed:22211086
- pubmed:22222724
- pubmed:22226087
- pubmed:22231575
- pubmed:22233654
- pubmed:25017682
- pubmed:28166217
- pubmed:29438107
- reaxys:5480511
- wikipedia.en:Lamivudine
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
Phenotype
Phenotype resulting from lamivudine
Phenotype where environments contain lamivudine
Phenotype modified by environments containing lamivudine
Phenotype affecting lamivudine
Human Disease Model