Search Ontology:
ChEBI
lamivudine
- Term ID
- CHEBI:63577
- Synonyms
-
- (-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
- (-)-2'-Deoxy-3'-thiacytidine
- 2',3'-Dideoxy-3'-thiacytidine
- 3'-Thia-2',3'-dideoxycytidine
- 3TC
- 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
- beta-L-2',3'-Dideoxy-3'-thiacytidine
- beta-L-3'-Thia-2',3'-dideoxycytidine
- Epivir
- lamivudine
- Definition
- A monothioacetal that consists of cytosine having a (2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl moiety attached at position 1. An inhibitor of HIV-1 reverse transcriptase, it is used as an antiviral in the treatment of AIDS and hepatitis B.
- References
-
- CAS:134678-17-4
- DrugBank:DB00709
- Drug_Central:1539
- KEGG:C07065
- KEGG:D00353
- LINCS:LSM-5215
- PDBeChem:3TC
- PMID:12135009
- PMID:19783232
- PMID:21465499
- PMID:21721935
- PMID:21851334
- PMID:22001270
- PMID:22028068
- PMID:22078148
- PMID:22085635
- PMID:22097898
- PMID:22098177
- PMID:22170540
- PMID:22211086
- PMID:22222724
- PMID:22226087
- PMID:22231575
- PMID:22233654
- PMID:25017682
- PMID:28166217
- PMID:29438107
- Patent:WO9117159
- Reaxys:5480511
- Wikipedia:Lamivudine
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_functional_parent
-
- has_role
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Phenotype
Phenotype resulting from lamivudine
Phenotype where environments contain lamivudine
Phenotype modified by environments containing lamivudine
Human Disease Model