Search Ontology:
ChEBI

masitinib

Term ID
CHEBI:63450
Synonyms
  • 4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)benzamide
  • AB 1010
  • AB-1010
  • AB1010
  • masitinib
Definition
A member of the class of benzamides that is the carboxamide resulting from the formal condensation of the carboxy group of 4-[(4-methylpiperazin-1-yl)methyl]benzoic acid with the primary amino group of 4-methyl-N3-[4-(pyridin-3-yl)-1,3-thiazol-2-yl]benzene-1,3-diamine. It is a highly selective oral tyrosine kinase inhibitor.
References
  • cas:790299-79-5
  • drugcentral:4791
  • lincs.smallmolecule:LSM-1130
  • pubmed:19549290
  • pubmed:19789626
  • pubmed:20033487
  • pubmed:20211560
  • pubmed:21034327
  • pubmed:21333567
  • pubmed:21504563
  • pubmed:21668810
  • reaxys:12083382
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from masitinib
Phenotype where environments contain masitinib
Phenotype modified by environments containing masitinib
Phenotype affecting masitinib
Human Disease Model