(2R,3S)-EHNA

Term ID

CHEBI:63058

Synonyms

(2R,3S)-3-(6-amino-9H-purin-9-yl)nonan-2-ol
(2R,3S)-3-(adenin-9-yl)-2-nonanol
(2R,3S)-9-(2-hydroxy-3-nonyl)adenine
(R,S)-6-amino-beta-hexyl-alpha-methyl-9H-purine-9-ethanol

Definition

EHNA of absolute configuration 2R,3S. Selective inhibitor of cGMP-stimulated phosphodiesterase (PDE2) (IC50 = 0.8 - 4 mM). Also a potent inhibitor of adenosine deaminase.

References

LINCS:LSM-2600

Ontology

ChEBI ( EBI )

Relationships

is a type of: EHNA

EHNA Show first 5 Terms
has_role: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor EC 3.5.4.4 (adenosine deaminase) inhibitor

EC 3.1.4.* (phosphoric diester hydrolase) inhibitor EC 3.5.4.4 (adenosine deaminase) inhibitor Show first 5 Terms
inverse is_conjugate_acid_of: (2R,3S)-EHNA(1+)

(2R,3S)-EHNA(1+) Show first 5 Terms
inverse is_enantiomer_of: (2S,3R)-EHNA

(2S,3R)-EHNA Show first 5 Terms
is_conjugate_base_of: (2R,3S)-EHNA(1+)

(2R,3S)-EHNA(1+) Show first 5 Terms
is_enantiomer_of: (2S,3R)-EHNA

(2S,3R)-EHNA Show first 5 Terms

Phenotype

Phenotype resulting from (2R,3S)-EHNA

Phenotype where environments contain (2R,3S)-EHNA

Phenotype modified by environments containing (2R,3S)-EHNA

Human Disease Model