metamizole

Term ID

CHEBI:62088

Synonyms

(antipyrinylmethylamino)methanesulfonic acid
[(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonic acid
[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonic acid
metamizol
metamizolum
N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)-N-methylaminomethanesulfonic acid

Definition

A pyrazole that is antiipyrine substituted at C-4 by a methyl(sulfomethyl)amino group, the sodium salt of which, metamizole sodium, was widely used as a powerful analgesic and antipyretic, but withdrawn from many markets from the 1970s due to a risk of causing risk of causing agranulocytosis.

References

cas:50567-35-6
drugbank:DB04817
drugcentral:4659
hmdb:HMDB0254502
kegg.drug:D08188
lincs.smallmolecule:LSM-5839
pubmed:11048407
pubmed:24724493
pubmed:29772595
pubmed:31435718
pubmed:32238269
pubmed:32588405
pubmed:33247375
pubmed:33675325
pubmed:33823317
pubmed:34038591
pubmed:34181748
pubmed:34273099
pubmed:34648192
pubmed:34726072
pubmed:35043434
pubmed:35138735
pubmed:35156383
pubmed:35275472
pubmed:35290991
pubmed:35416155
pubmed:35416465
pubmed:35433049
pubmed:35584441
pubmed:35670337
pubmed:35774740
pubmed:35774878
pubmed:35912424
pubmed:35933233
reaxys:327442
wikipedia.en:Metamizole

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from metamizole

Phenotype where environments contain metamizole

Phenotype modified by environments containing metamizole

Phenotype affecting metamizole

Human Disease Model