Search Ontology:
ChEBI

ketorolac tromethamine

Term ID
CHEBI:6130
Synonyms
  • 1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate
  • Acular
  • Acuvail
  • Dolac
  • Lixidol
  • Sprix
  • Toradol
Definition
An organoammonium salt resulting from the mixture of equimolar amounts of ketorolac and tromethamine (tris). It has potent non-sedating analgesic and moderate anti-inflammatory effects. It is used in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.
References
  • cas:74103-07-4
  • drugbank:DB00465
  • hmdb:HMDB0014608
  • kegg.drug:D00813
  • pubmed:19663721
  • pubmed:23016110
  • pubmed:23098098
  • pubmed:23199134
  • pubmed:23302965
  • pubmed:23992042
  • pubmed:8863973
  • reaxys:6463165
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from ketorolac tromethamine
Phenotype where environments contain ketorolac tromethamine
Phenotype modified by environments containing ketorolac tromethamine
Phenotype affecting ketorolac tromethamine
Human Disease Model