Search Ontology:
ChEBI
fluprostenol
- Term ID
- CHEBI:60782
- Synonyms
-
- EINECS 255-029-3
- fluprostenol
- fluprostenolum
- ICI 81,008
- rac-(5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl]hept-5-enoic acid
- travoprost acid
- travoprost free acid
- Definition
- An organofluorine compound that is racemic prostaglandin F2α in which the pentyl group is replaced by a 3-(trifluoromethyl)phenoxymethyl group. A synthetic analogue of prostaglandin F2α, ophthalmic solutions of its isopropyl ester prodrug, travoprost, are used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. The isopropyl ester group of travoprost is hydrolysed to the biologically active free acid by esterases in the cornea.
- References
-
- cas:40666-16-8
- pubmed:11832489
- pubmed:11929662
- pubmed:550147
- pubmed:6090118
- pubmed:6911921
- pubmed:6916556
- pubmed:941381
- pubmed:951924
- reaxys:8368795
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from fluprostenol
Phenotype where environments contain fluprostenol
Phenotype modified by environments containing fluprostenol
Phenotype affecting fluprostenol
Human Disease Model