isotretinoin

Term ID

CHEBI:6067

Synonyms

• (2Z,4E6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
• (7E,9E,11E,13Z)-retinoic acid
• 13-cis-retinoic acid
• 13-cis-Vitamin A acid
• 13-RA
• Accutane
• Amnesteem
• cis-RA
• Claravis
• isotretinoin
• isotretinoina
• isotretinoine
• isotretinoino
• isotretinoinum
• Neovitamin A acid

Definition

A retinoic acid that is all-trans-retinoic acid in which the double bond which is α,β- to the carboxy group is isomerised to Z configuration. A synthetic retinoid, it is used for the treatment of severe cases of acne and other skin diseases.

References

• cas:4759-48-2
• drugbank:DB00982
• drugcentral:1508
• hmdb:HMDB0006219
• kegg.drug:D00348
• lipidmaps:LMPR01090021
• patent:EP111325
• patent:US4556518
• pubmed:11606947
• pubmed:11866680
• pubmed:15304471
• pubmed:18077132
• pubmed:18788179
• pubmed:19568610
• pubmed:20482692
• pubmed:23676507
• pubmed:9807973
• reaxys:1885770
• wikipedia.en:Isotretinoin

Ontology

ChEBI  ( EBI )

Resources

CTD